Every Animal Deserves a Second Chance.
At Palmetto Animal League, we rescue, heal, and rehome dogs and cats in need, while supporting our community through affordable vet care and our local thrift store. Together, we’re building a compassionate Lowcountry where every neglected animal has a chance to thrive.
Our Sponsors
Our Mission:
To build a community where every neglected animal has a second chance at life guided by compassion, proactive rescue, and responsible population management.
For over 15 years, we’ve been dedicated to helping animals find love, safety, and a home to call their own. Through our rescue center, subsidized veterinary clinic, and thrift store, we’re able to give hope to animals in need and the people who care about them.
One Mission. Three Ways to Make a Difference.
We operate through three connected programs that work hand-in-hand to support our rescue efforts. Our adoption center gives animals a safe place to heal and find homes, while our veterinary clinic and thrift store provide sustainable community support and essential funding.
Adoption & Rescue Center
Where second chances begin.
Our dedicated team works tirelessly to rescue, rehabilitate, and rehome dogs and cats from neglect, abandonment, and overcrowded shelters. Every adoption opens space for another life to be saved.
Affordable Veterinary Clinic
Every Pet. Every Family.
Our affordable veterinary clinic helps local pet owners access vital services like vaccinations, spay/neuter, and wellness exams, preventing suffering & keeping animals out of shelters.
Thrift Store
Shop with purpose.
Every purchase and donation at our thrift store directly supports animal rescue efforts. Find great deals, give items a second life, and help fund the care of dogs and cats in need.
Your Support Makes an Impact.
2,400+
Animals rescued last year
5,000+
Affordable vet visits provided
1,200+
Successful adoptions
50,000+
Thrift store donations accepted
Each number represents a life changed, and none of it would be possible without people like you.
Second Chances, Forever Homes
Every adoption tells a story of hope. From scared and abandoned to happy and loved, these transformations remind us why we do what we do every single day.
The Lesane family
— Pet Adopter
I hope this message finds you well. I wanted to reach out and share a wonderful update, along with some photos of our sweet Betty. From the moment Betty joined our family, she has brought a burst of love and energy into our home. Her gentle spirit and playful nature have made such an incredible difference, and we truly couldn’t be more grateful.
As you know, we lost our soul dog Scotty after twelve beautiful years together, and the past few months have been incredibly difficult for all of us. Our other baby, Sophia, was especially heartbroken and struggling to cope with the loss. It was heartbreaking to see her so down, but Betty has been a remarkable companion. She has lifted Sophia’s spirits, rekindled her playfulness, and brought light back into her eyes. The transformation has been amazing—Sophia is so much happier, and our home feels whole again.
We are deeply thankful to the PAL team for bringing Betty into our lives. Your efforts have truly made a difference, not just for Betty, but for our entire family. Thank you for everything you do and for helping us find such a perfect match.
Sending lots of gratitude and puppy hugs your way!
Warmly,
The Lesane family
Meg Zalewski
— Pet Fosterer
I am so thankful to be volunteer for Palmetto Animal League. My journey began before 2010 when I met with the now president of PAL, Amy Campanini. A friend introduced me to her as a person who helps save homeless animals. She had organized a group of people to care for these animals by fostering them in their homes, pooling resources, and keeping these sweet souls out of shelters that euthanize for space. Out of that group grew the dream that is now a reality. A physical building and people who believe every abandoned, neglected and homeless animal deserves a safe nurturing place to reside while they wait for a second chance at a loving and safe home. I have fostered pregnant cats and watched them and their kittens grow into happy and lovable pets. I have also fostered scared cats that have blossomed into loving and trusting companions. From bottle feeding to socializing to medical recuperation, I have been able to do all these things because the PAL family strives to be the best stewards for the animals in their care. PAL also provides support in the way of food, medication, materials and guidance for all foster families free of charge. My first cat from PAL was a terrified grey tuxedo named Socks. He had been found abandoned with his siblings. I doubt there would be many organizations that would have taken in such a “spicy” little kitten. As his foster mom, I had a chance to see him grow into a cuddle bug who loved to fetch and return a ball to my husband. We decided to adopt him and make him a permanent part of our family. Since then my home has averaged ten foster cats a year and I have witnessed my fosters move into their forever homes with their new families. All of this was possible due to the love, compassion, and dedication of the PAL family. The experience of being a PAL foster has enriched my life beyond measure and proven a second chance at love and life are within reach for people as well as our animal companions.
Masaryk Family
— Pet Adopter
We adopted our dog Bingo from Palmetto Animal League in July. After suddenly losing our 1 year old dog who we got through a breeder, we knew a dog was still meant to be a part of our family and decided to go the adoption route. After visiting all of the local shelters we found Bingo at Palmetto animal with two other of his siblings. They were just 3 months old.This was a classic case of the dog choosing us. After sitting down on the floor to see the three pups Bingo instantly came over and fell asleep in my daughter’s lap. Two days later we brought him home and he has been the perfect addition to our family ever since. He has been the sweetest dog who loves nothing more than being close to his family. Especially my two children. He watches and protects them like they were his own. He has brought so much happiness to my children and they cannot wait to see him everyday they get home from school. And Bingo is always there waiting for them with his tail wagging 100mph and 100 kisses each for them. Palmetto Animal League made the adoption process an ease and even sent us home with a goody bag including some of the food he was being fed while at the shelter. It is clear how much they care for the animals that are with them and how much work goes into making sure all of their animals are healthy and ready for new homes.
Be Part of Their Second Chance.
There are so many ways to make a difference, whether you give your time, your resources, or your heart. Volunteer at our shelter, foster a pet in need, donate gently used goods to our thrift store, or join our monthly giving program. Every act of kindness helps save lives.
What’s Happening at Palmetto Animal League
From adoption events to thrift store sales and low-cost vaccine clinics, there’s always something happening in our community.
We believe in giving pets second chances and happy homes.
Together, We Can Save More Lives.
Every day, animals arrive at our doors scared, hungry, and in need of care. Your donation gives them food, medical treatment, and most importantly hope. 100% of your gift stays local, helping animals right here in our community.
